Systemic contact dermatitis of the eyelids caused by formaldehyde derived from aspartame?

نویسندگان

  • A Michele Hill
  • Donald V Belsito
چکیده

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Formaldehyde, aspartame, and migraines: a possible connection.

Aspartame is a widely used artificial sweetener that has been linked to pediatric and adolescent migraines. Upon ingestion, aspartame is broken, converted, and oxidized into formaldehyde in various tissues. We present the first case series of aspartame-associated migraines related to clinically relevant positive reactions to formaldehyde on patch testing.

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Doubtful value of patch testing for suspected contact allergy to ophthalmic products.

Sir, Allergic contact dermatitis is the most common cause of peri-orbital eczema (1). It may be caused by allergens brought in contact with the eyelids by hand transfer (like toluene sulfonamide-formaldehyde resin in nail polishes), by airborne contact (like sesquiterpene lactones) or, most frequently, by direct application of cosmetics or topical ophthalmic medicaments. The percentage of sensi...

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Formaldehyde is a colorless gas with a pungent odor that is widely used as a preservative in toiletries and cosmetics and in products for household and industrial use. Both formaldehyde itself and substances that can release it are a common cause of allergic contact dermatitis. This condition often becomes chronic, given that these allergens are found nearly everywhere and it is difficult for p...

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P-tert-butylphenol-formaldehyde resin is a widely used adhesive chemical. It is used in a broad range of products and should be kept in mind when encountering children with suspected allergic contact dermatitis. We present a girl who developed contact allergy to p-tert-butylphenol-formaldehyde resin used in orthopedic braces.

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For surface disinfection in hospitals and nursing homes, preparations containing aldehydes such as formaldehyde, glutaral, or glyoxal, as well as quaternary ammonium compounds (QACs), are being used. Occupational allergic contact dermatitis (OACD), including airborne dermatitis, caused by these compounds is a well-known problem in nurses and hospital cleaners (1–6). For diagnostic purposes, onl...

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عنوان ژورنال:
  • Contact dermatitis

دوره 49 5  شماره 

صفحات  -

تاریخ انتشار 2003